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Muscle Disease - Pathology and Genetics (2nd Ed)(gnv64)

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Muscle Disease: Pathology and Genetics (2nd Ed)
by Hans H. Goebel, Caroline
A. Sewry and Roy O. Weller
Wiley-Blackwell | August 2013 | ISBN-10: 0470672056 | PDF | 392 pages | 30.2 mb
http://www.amazon.com/Muscle-Disease-Pathology-Hans-Goebel/dp/0470672056

This book clarifies the pathology
and genetics of muscle disease for pathologists, clinicians, geneticists and researchers to aid in the diagnosis and
management of patients. Organized around the 'motor unit' concept, this book presents the latest understanding of muscle
disease, and how this can help identify new treatments.
Written by more than 60 international experts in the field,
Muscle Disease embodies the explosion of new concepts and information on the pathology and genetics of muscle disease
that has occurred in recent years.
In order to accommodate the new complex principles involved, the book is
organized around the motor unit and the inherited disorders, in particular, are centered on the ultrastructure and
organelles within the muscle fiber.  In this way, the wide spectrum of muscle diseases, ranging from neurogenic and
inflammatory disorders to those involving defects in a single gene, can be expressed in a logical sequence.  For
example, disorders that principally involve specific organelles or particular metabolic processes are grouped together,
with sections on disorders of the sarcolemma, mitochondria, myofibrils, glycogen and lipid metabolism, etc.  Firm
reference to clinical aspects and classification of muscle diseases has been maintained throughout the book with an
initial clinical overview and with specific clinical sections in each chapter.  For ease of navigation through the
complex variety of muscle diseases, each chapter has been organized in a standard pattern that allows the reader to
easily locate information on individual disease entities in different chapters.
This new edition of Muscle Disease:
Pathology and Genetics will be a very valuable resource for clinicians, pathologists, geneticists and basic
neuroscientists involved in diagnosis, research, treatment and management of patients with muscle disease.

About the Editors
Hans H. Goebel, MD, Professor of Neuropathology, Charité – Universitätsmedizin
Berlin, Berlin, Germany; Department of Neuropathology, Johannes Gutenberg University, Mainz, Germany,
Caroline A.
Sewry, PhD, FRCPath, Professor of Muscle Pathology, Dubowitz Neuromuscular Centre, Institute of Child Health and Great
Ormond Street Hospital, London, UK; Wolfson Centre for Inherited Neuromuscular Diseases, RJAH Orthopaedic Hospital,
Oswestry, UK
Roy O. Weller, MD, PhD, FRCPath, Emeritus Professor of Neuropathology, Clinical Neurosciences,
University of Southampton School of Medicine, Southampton General Hospital, Southampton, UK

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